پژوهشگاه پلیمر و پتروشیمی ایران با همکاری انجمن پلیمر ایران مجله علوم و تکنولوژی پلیمر 10163255 20 6 2008 02 20 Surface Coating of Islets of Langerhans by Activated Polyethylene Glycol پوشش دهی سطح سلول های جزایر لانگرهانس با پلی اتیلن گلیکول فعال شده 529 538 737 10.22063/jipst.2008.737 FA سمیره هاشمی نجف آبادی ابراهیم واشقانی فراهانی عباس شجاع الساداتی یاسوهیرو ایواناگا Journal Article 2013 02 24 The final treatment for diabetes is transplantation of islets of Langerhans. One of the new proposed methods for immunological preservation of transplanted cells is coating of cell surface by polyethylene glycol. In this study, the surface of islets of Langerhans was coated by cyanuric chloride activated methoxy polyethylene glycol. The effect of polymer coating, at two different reaction times and polymer concentrations, by immunological and morphological tests on the cells, was studied. A decrease of 47-76.5% in the immunological response against the coated cells, in comparison to control<br />samples, was observed. Also, morphologically, these coated cells were more stable. http://jips.ippi.ac.ir/article_737_5262f7c9432912207c33a8f949a357ee.pdf