نوع مقاله : مروری
نویسندگان
1 رضوانشهر، دانشگاه تهران، دانشکدگان فنی، دانشکده فنی کاسپین ، گروه مهندسی پلیمر، صندوق پستی 119-43841
2 تگزاس، دانشگاه بین المللی A&M تگزاس، گروه زیست شناسی و شیمی
3 رشت، دانشگاه علوم پزشکی گیلان، مرکز تحقیقات سوختگی و ترمیمی، کد پستی 4193713194
چکیده
کلیدواژه‌ها
موضوعات
عنوان مقاله [English]
نویسندگان [English]
B Bleeding is a dangerous factor for human health due to accidents. As a result of severe bleeding, the function of some organs may be disturbed or even lead to death. The most widely used method to treat people who lose a lot of blood is blood transfusion, but this method has complications such as acute hemolytic reaction caused by blood transfusion, fever, chills, skin sensitivity, and transmission of infectious agents and viruses. Therefore, the most effective method to prevent blood loss in patients is methods to prevent bleeding. In recent years researchers have turned towards dressings that, in addition to healing the wound and reducing the rate of infection, can increase the speed of blood coagulation. In addition, in surgeries and emergency situations, a blood coagulant can save the lives of many people. The process of coagulation and healing of a wound consists of several coordinated stages, the first stage of which is to stop bleeding, the next stages of healing are inflammation, proliferation, and regeneration in order. For this purpose two types of regenerated and non-regenerated cellulose of plant and bacterial origin have been used in bleeding coagulation applications, and according to the reported results, the regenerated cellulose has superior coagulation properties. One of the ways to increase the coagulation efficiency in regenerated cellulose is its oxidation. During the oxidation process, the speed and performance of coagulation increase due to the increase of carboxyl groups. Two measures of clot formation time and amount of bleeding are commonly used to evaluate coagulation function. Factors that can affect the performance of these materials include the origin, type of cellulose regeneration and oxidation process. In this research, different methods of regeneration, oxidation performance evaluation methods, amount of blood lost, clot coagulation time, animal and cell tests related to oxidized cellulose as a biocompatible and biodegradable binder have been investigated.
کلیدواژه‌ها [English]
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